Title of article :
A convenient method for N-1 arylation of uracil derivatives
Author/Authors :
Andrzej Gondela، نويسنده , , Andrzej and Walczak، نويسنده , , Krzysztof، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
1-(4-Nitrophenyl)- and 1-(2,4-dinitrophenyl)uracil derivatives have been obtained by direct arylation of uracil and its 5-substituted derivatives using 1-fluoro-4-nitrobenzene or 1-fluoro-2,4-dinitrobenzene in the presence of a base. The application of the newly obtained uracil derivatives in further synthesis is also presented.
Keywords :
1-(2 , ANRORC type reaction , 4-Dinitrophenyl)-5-nitrouracil , nucleophilic aromatic substitution , 5-Substituted uracil derivatives , 5-Nitro-1-(4-nitrophenyl)uracil
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters