Title of article :
Studies directed towards the synthesis of antascomicin A: stereoselective synthesis of the C22–C34 fragment of the molecule
Author/Authors :
Chakraborty، نويسنده , , Tushar Kanti and Mohan، نويسنده , , Bajjuri Krishna and Sreekanth، نويسنده , , Midde، Manoranjan نويسنده Department of Infectious Diseases, Rural Development Trust Hospital, Bathalapalli, AP, India ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
A stereoselective synthesis of the C22–C34 fragment of the non-immunosuppressive immunophilin-binding natural product, antascomicin A was achieved using d-quinic acid as the starting material and highly stereoselective aldol reactions were employed, as key steps, to build the remaining stereocentres at C23, C26 and C27.
Keywords :
aldol reaction , Antascomicin , immunosuppressant , FKBP12 binding ligand
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
