Title of article :
Preparation of 2,3-dihydro-1H-spiro[isoquinoline-4,4′-piperidine] via an N-sulfonyl Pictet–Spengler reaction
Author/Authors :
Liu، نويسنده , , Jian and Jian، نويسنده , , Tianying and Sebhat، نويسنده , , Iyassu and Nargund، نويسنده , , Ravi، نويسنده ,
Abstract :
A high yielding synthesis of variously substituted 2,3-dihydro-1H-spiro[isoquinoline-4,4′-piperidine] is reported. N-(2-nitrophenyl)sulfonyl was successfully used as both an activating and protecting group for the key Pictet–Spengler reaction.
