Title of article
Asymmetric indium-mediated synthesis of homopropargylic alcohols
Author/Authors
Hirayama، نويسنده , , Lacie C. and Dunham، نويسنده , , Kevin K. and Singaram، نويسنده , , Bakthan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
5173
To page
5176
Abstract
A method for the enantioselective synthesis of homopropargylic alcohols using indium under Barbier-like conditions is reported herein. Both aromatic and aliphatic aldehydes were successfully converted to the corresponding homopropargylic alcohols in good yield and high enantiomeric excesses using propargyl bromide, indium, and (1S,2R)-(+)-2-amino-1,2-diphenylethanol as a chiral auxiliary.
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1851373
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