Title of article
A mild, one-pot synthesis of disubstituted benzimidazoles from 2-nitroanilines
Author/Authors
Hornberger، نويسنده , , Keith R. and Adjabeng، نويسنده , , George M. and Dickson، نويسنده , , Hamilton D. and Davis-Ward، نويسنده , , Ronda G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
3
From page
5359
To page
5361
Abstract
A one-pot synthesis of disubstituted benzimidazoles from 2-nitroanilines is described. Hydrogenation of N-substituted 2-nitroanilines with palladium on carbon as catalyst in the presence of trimethyl orthoformate and catalytic pyridinium p-toluenesulfonate (PPTS) at room temperature provided good to excellent yields of the corresponding disubstituted benzimidazoles.
Keywords
Benzimidazoles , Hydrogenation , cyclocondensation
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1851488
Link To Document