Title of article :
γ-Heteroatom directed stereocontrolled Staudinger cycloaddition reaction of vinylketenes and imines
Author/Authors :
Shaikh، نويسنده , , Aarif L. and Puranik، نويسنده , , Vedavati G. and Deshmukh، نويسنده , , A.R.A.S.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
Vinylketenes possessing a γ-heteroatom, on Staudinger cycloaddition reaction with imines gave trans-3-vinyl-β-lactams in very good yields. The vinyl side chain stereoselectively adopts the Z-configuration in the transition state to stabilize the vinylketene and produces, exclusively, trans-3-vinyl-β-lactams.
Keywords :
Staudinger reaction , stereoselective synthesis , Vinylketenes , imines
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
