Title of article :
First lipase catalysed resolution of epoxy enol esters
Author/Authors :
JH Gravil، نويسنده , , Sébastien and Veschambre، نويسنده , , Henri and Chênevert، نويسنده , , Robert G. Bolte، نويسنده , , Jean، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
We report the first enzyme-catalysed kinetic resolution of epoxy enol esters. The lipase-promoted hydrolysis of these compounds provided α-hydroxyketones or α-hydroxyaldehydes (arising from the spontaneous rearrangement of the epoxy enols) and the residual esters with moderate to good enantioselectivity (E up to 100).
Keywords :
enzyme catalysis , Hydrolases , kinetic resolution , Hydrolysis , Epoxy enol esters
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
