Title of article
An efficient protocol for solid phase aminothiazole synthesis
Author/Authors
K.G. Sreejalekshmi، نويسنده , , Kumaran G. and Devi، نويسنده , , Satyabhama K.C. and Rajasekharan، نويسنده , , Kallikat N.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
6179
To page
6182
Abstract
An efficient synthesis of 2,4-diamino-5-ketothiazoles under solid phase conditions has been achieved by the reaction of polymer supported amidinothioureas with α-haloketones. This novel synthetic approach involving traceless cleavage from the support is suited for automation, and allows solid phase combinatorial synthesis of 2,4-diamino-5-ketothiazoles in good yields and purities.
Keywords
2 , 4-Diamino-5-ketothiazoles , Solid phase synthesis , Thiocarbamoylamidine transfer , Traceless cleavage , Aminomethylpolystyrene
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1852118
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