Title of article :
A one-pot synthesis of novel sugar derived 5,6-dihydro-quinazolino[4,3-b]quinazolin-8-ones: an entry towards highly functionalized sugar-heterocyclic hybrids
Author/Authors :
Roy، نويسنده , , Abhijeet Deb and Subramanian، نويسنده , , Arunachalam and Mukhopadhyay، نويسنده , , Balaram and Roy، نويسنده , , Raja، نويسنده ,
Abstract :
An efficient and practical one-pot method for the synthesis of novel diversified sugar derived dihydro-quinazolino[4,3-b]quinazolin-8-ones has been reported. Various protected sugar hemiacetals were used to synthesize the hybrid tetracyclic ring system. The one-step reductive transformation of 2-(2-nitrophenyl)-3H-quinazolin-4-one with different sugar hemiacetals furnished the desired tetracyclic product in good yields and with high purity.
