Title of article :
Solid-phase synthesis of 4-biaryl-piperidine-4-carboxamides
Author/Authors :
Zhu، نويسنده , , Jin and Pottorf، نويسنده , , Richard S. and Player، نويسنده , , Mark R.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
A novel solid-phase synthesis of 4-biaryl-piperidine-4-carboxamides has been developed using FDMP resin with a carboxamide as the anchor point. With this approach, three points of diversity were incorporated into a GPCR-directed scaffold. Final products were obtained in good purity and yield.
Keywords :
solid-phase , Suzuki coupling , Biaryl-piperidine
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
