Title of article :
Asymmetric induction in the reactions of 3-aryl-1,2,4-triazin-5(4H)-ones with C-nucleophiles
Author/Authors :
Egorov، نويسنده , , Ilya N. and Zyryanov، نويسنده , , Grigory V. and Ulomsky، نويسنده , , Eugeny N. and Rusinov، نويسنده , , Vladimir L. and Chupakhin، نويسنده , , Oleg N.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
3-Aryl-1,2,4-triazin-5(4H)-ones, in the presence of N-protected amino acids, react with C-nucleophiles to form 1-acyl-6-Nu-3-aryl-1,6-dihydro-1,2,4-triazin-5(4H)-ones in high diastereomeric excess. This is the first case of the use of amino acids as chiral auxiliaries in nucleophilic additions to triazinones.
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
