Title of article :
Ti(II)-mediated domino cyclization of 2-functionalized 1-halo-2,n-enynes (n = 7, 8) to bicyclic compounds
Author/Authors :
Okamoto، نويسنده , , Sentaro and Ito، نويسنده , , Hidemoto and Tanaka، نويسنده , , Shogo and Sato، نويسنده , , Fumie، نويسنده ,
Abstract :
The reaction of 2-functionalized 1-halo-2,n-enynes (n = 7 or 8) with a divalent titanium reagent, Ti(O-i-Pr)4/2i-PrMgCl, proceeded in a domino fashion to afford bicyclic compounds in good yields.
