Author/Authors :
Filipski، نويسنده , , Kevin J. and Kohrt، نويسنده , , Jeffrey T. and Casimiro-Garcia، نويسنده , , Agustin and Van Huis، نويسنده , , Chad A. and Dudley، نويسنده , , Danette A. and Cody، نويسنده , , Wayne L. and Bigge، نويسنده , , Christopher F. and Desiraju، نويسنده , , Shrilakshmi and Sun، نويسنده , , Shaoyi and Maiti، نويسنده , , Samarendra N. and Jaber، نويسنده , , Mohamad R. and Ed، نويسنده ,
Abstract :
A robust method has been developed to couple a wide variety of pyridin-2-ones and aryl halides. This C–N bond forming reaction makes use of catalytic copper(I) iodide and the ligand 8-hydroxyquinoline. These conditions tolerate a wide degree of functionality on both the aryl halide and pyridin-2-one reactants and have resulted in numerous examples being synthesized.
