Author/Authors :
Csuk، نويسنده , , René and Schmuck، نويسنده , , Kianga and Schنfer، نويسنده , , Renate، نويسنده ,
Abstract :
A new synthetic route for the synthesis of betulinic acid from betulin has been developed. The main step of this procedure is the selective oxidation of the primary alcohol function of betulin without affecting the secondary hydroxyl group. Applying shorter reaction times and lower temperatures results in the exclusive formation of the corresponding aldehyde, betulinal.