Author/Authors :
Dehlinger، نويسنده , , Véronique and Cordier، نويسنده , , Frédéric and Dell، نويسنده , , Colin P. and Dreyfus، نويسنده , , Nicolas and Jenkins، نويسنده , , Nikki and Sanderson، نويسنده , , Adam J. and Smith، نويسنده , , Colin W.، نويسنده ,
Abstract :
An efficient methodology for the synthesis of complex pyridin-3-yl-phenyl biaryl systems is described; microwave irradiation greatly enhances the rate of the two Pd-catalyzed key steps: formation of the stannane partner and its subsequent Stille coupling with a range of highly functionalized pyridines. Besides being fast and high yielding, this process also allows diversification of the pyridine at a late stage.