Author/Authors :
Evdokimov، نويسنده , , Nikolai M. and Kireev، نويسنده , , Artem S. and Yakovenko، نويسنده , , Andrey A. and Antipin، نويسنده , , Mikhail Yu. and Magedov، نويسنده , , Igor V. and Kornienko، نويسنده , , Alexander، نويسنده ,
Abstract :
Benzopyrano[2,3-b]pyridine is an important privileged medicinal scaffold. A three-component reaction of salicylaldehydes, thiols and 2 equiv of malononitrile that leads to the formation of a series of compounds incorporating 2,4-diamino-3-cyano-5-sulfanylbenzopyrano[2,3-b]pyridine framework is described. A proposed mechanism with the supporting experimental data is presented.
