Author/Authors :
Shetty، نويسنده , , Rupa and Nguyen، نويسنده , , Duyan and Flubacher، نويسنده , , Dietmar and Ruggle، نويسنده , , Franziska and Schumacher، نويسنده , , Andreas and Kelly، نويسنده , , Martha and Michelotti، نويسنده , , Enrique، نويسنده ,
Abstract :
A regioselective synthesis of 2,4,6-trisubstituted pyridine is described starting from 2,6-dibromo-4-nitropyridine. All three different regioisomers of the 2,4,6-triamino substituted pyridine have been synthesized in four to five steps. The method described is a general route to unsymmetrical 2,4,6-trisubstituted amino pyridines.