Title of article
Studies toward the total synthesis of irumamycin: stereoselective preparation of the C(15)–C(27) segment via two-directional chain synthesis
Author/Authors
Hirose، نويسنده , , Tomoyasu and Sunazuka، نويسنده , , Toshiaki and Yamamoto، نويسنده , , Daisuke and Mouri، نويسنده , , Mutsumi and Hagiwara، نويسنده , , Yoshiaki and Matsumaru، نويسنده , , Takanori and Kaji، نويسنده , , Eisuke and ?mura، نويسنده , , Satoshi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
413
To page
416
Abstract
The basic structure of the C(15)–C(27) part of irumamycin (1) was synthesized. Stereoselective assembly of C16, 17, 22, and an extra C21 stereocenter was achieved by two-directional Brown’s asymmetric allyl boration. Group selective PMP acetal formation and oxidative cleavage of vinyl group facilitated the differentiation of the ends of a two-directionally synthesized chain.
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1853954
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