Author/Authors :
Tomasevich، نويسنده , , Laura L. and Kennedy، نويسنده , , Nicole M. and Zitelli، نويسنده , , Stephen M. and Troy Hull II، نويسنده , , R. and Gillen، نويسنده , , Chelsey R. and Lam، نويسنده , , Suet K. and Baker، نويسنده , , Neal J. and Rohanna، نويسنده , , John C. and Conley، نويسنده , , Jason M. and Guerra، نويسنده , , Marcy L. and Starr، نويسنده , , Mari Lynne and Sever، نويسنده , , Justine B. ، نويسنده ,
Abstract :
Condensation of ninhydrin with tryptamide or tryptamine followed by Lewis acid-induced rearrangement provided yohimbanones that were readily converted to β-carbolines via oxidative ring cleavage. The analogous condensation-rearrangement with 3,4-dimethoxyphenethylamine and ninhydrin afforded an oxyprotoberberine, which was further oxygenated at the 13a position.
