Efficient synthesis of the selective COX-2 inhibitor GW406381X
Author/Authors :
Whitehead، نويسنده , , Andrew J. and Ward، نويسنده , , Richard A. and Jones، نويسنده , , Martin F.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Pages :
3
From page :
911
To page :
913
Abstract :
An efficient synthesis of the selective COX-2 inhibitor GW406381X is described via a novel intramolecular Mannich-type cyclisation to construct the pyrazolo-[1,5a]-pyridazine heterocyclic core.