Title of article :
Direct reductive amination of carbonyl compounds using bis(triphenylphosphine) copper(I) tetrahydroborate
Author/Authors :
Bhanushali، نويسنده , , Mayur J. and Nandurkar، نويسنده , , Nitin S. and Bhor، نويسنده , , Malhari D. and Bhanage، نويسنده , , Bhalchandra M.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
A direct reductive amination protocol for aldehydes/ketones using bis(triphenylphosphine) copper(I) tetrahydroborate as a novel reducing agent in the presence of sulfamic acid has been developed. The reagent chemoselectively reduces the imine moiety and does not affect other reducible functionalities such as chloro, nitro, cyano and methoxy.
Keywords :
Amines , reductive amination , Bis(triphenylphosphine) copper(I) tetrahydroborate , carbonyl compounds
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters