Title of article :
Synthesis of chloroquinocin, a pyranonaphthoquinone antibiotic against Gram-positive bacteria
Author/Authors :
Akiko Shimbashi، نويسنده , , Akiko and Nishiyama، نويسنده , , Shigeru، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
Chloroquinocin 1 is an antimicrobial agent against Gram-positive bacteria, including MRSA (methicillin-resistant Staphylococcus aureus). A successful synthesis of 1 was attained through a unique chlorination of the corresponding naphthoquinone derivative 12 as a key step.
Keywords :
Methicillin-resistant Staphylococcus aureus , antibiotic , Gram-positive bacteria , Chlorination , Pyranonaphthoquinone , Chloroquinocin
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
