Author/Authors :
Raynal، نويسنده , , Nicolas and Averlant-Petit، نويسنده , , Marie-Christine and Bergé، نويسنده , , Gilbert and Didierjean، نويسنده , , Claude and Marraud، نويسنده , , Michel and Duru، نويسنده , , Christiane and Martinez، نويسنده , , Jean and Amblard، نويسنده , , Muriel، نويسنده ,
Abstract :
Oligomers derived from dipeptide mimics were selected by computational study for their suitability to fold in ordered structures. After selection of a monomeric unit, short oligomers were synthesized and analyzed by NMR and IR. Oligomers built from 2-aminomethyl-phenyl-acetic acid were shown to adopt a helical structure stabilized by 10-membered ring hydrogen bonds.
Keywords :
Poly(AMPA) , molecular modeling , Dipeptide mimics , 1H NMR and IR studies , Helical oligomers