Glycosylative transcarbamylation: efficient transformation of tert-butyl carbamates to novel glycoconjugates

Reaction of a variety of tert-butyl carbamates under glycosylation conditions gives rise to anomeric 2-deoxy-2-amino sugar carbamates in a good to excellent yields. The reaction exhibits good tolerance to several common protecting groups, and has been used to generate unnatural glycopeptide building blocks.