Title of article
Sequential peptide ligation by using a controlled cysteinyl prolyl ester (CPE) autoactivating unit
Author/Authors
Kawakami، نويسنده , , Toru and Aimoto، نويسنده , , Saburo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
3
From page
1903
To page
1905
Abstract
A peptide building block containing a cysteinyl prolyl ester (CPE) autoactivating unit was ligated with a cysteinyl peptide under native chemical ligation conditions. The CPE autoactivating function can be controlled by the protection of the thiol group, permitting the selective ligation of the peptide building block at either the C or N terminus.
Keywords
CPE autoactivating unit , Controlled sequential ligation , Peptide ligationPeptide thioester
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1854444
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