Author/Authors :
Goh، نويسنده , , Wai Kean and Iskander، نويسنده , , George and Black، نويسنده , , David StC and Kumar، نويسنده , , Naresh، نويسنده ,
Abstract :
A new versatile method for the conversion of fimbrolides to the corresponding novel dihydropyrrol-2-ones is described. This new efficient lactamization protocol has the advantage of higher yields and can be used for the synthesis of a series of new dihydropyrrol-2-ones with interesting anti-bacterial properties.