Author/Authors :
Zhang، نويسنده , , Fuyao and Mitchell، نويسنده , , David and Pollock، نويسنده , , Patrick and Zhang، نويسنده , , Tony Y.، نويسنده ,
Abstract :
An efficient synthesis of 2-bromo-3-aryloxybenzothiophene derivatives by a conjugate addition–elimination sequence of 2,3-dibromo benzothiophene dioxides with phenolic nucleophiles has been developed. These benzothiophene derivatives serve as important intermediates for the synthesis of SERM analogues.