Title of article
Lewis and Brönsted acid catalyzed Friedel–Crafts hydroxyalkylation of mucohalic acids: a facile synthesis of functionalized γ-aryl γ-butenolides
Author/Authors
Zhang، نويسنده , , Ji and Blazecka، نويسنده , , Peter G. and Curran، نويسنده , , Timothy T.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
2611
To page
2615
Abstract
A catalytic, green and practical method for Friedel–Crafts hydroxyalkylation of mucohalic acid has been accomplished. Reaction of mucohalic acids with various electron-rich aromatic compounds in the presence of catalytic (1 mol % to 10 mol %) In(OTf)3 or Brönsted acid, such as H2SO4 in acetic acid provides γ-aryl γ-butenolides in moderate to excellent yield.
Keywords
Friedel–Crafts hydroxyalkylation , Mucochloric acid , Mucobromic acid , Indium(III) salt , green chemistry
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1854688
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