Author/Authors :
Gesenberg، نويسنده , , Kirsten and Deshpande، نويسنده , , Prashant P. and Pullockaran، نويسنده , , Annie and Xu، نويسنده , , Feng and Wu، نويسنده , , Dedong and Gao، نويسنده , , Qi and Pathirana، نويسنده , , Charles and Castoro، نويسنده , , John and Soundararajan، نويسنده , , Nachimuthu and Staab، نويسنده , , Andrew، نويسنده ,
Abstract :
Transformation of 4,7-dimethoxy-6-azaindole into 4-hydroxy-7-methoxy-6-azaindole or 7-hydroxy-4-methoxy-6-azaindole can be readily controlled by careful selection of a reagent. Treatment with concentrated HCl results in hydrolysis at the 4-position exclusively, while TMS-I provides demethylation at the 7-position only. Products were unambiguously identified by single crystal X-ray crystallography.
