Title of article :
Asymmetric dehydration of β-hydroxy esters via kinetic resolution
Author/Authors :
Kim، نويسنده , , Yongtae and Choi، نويسنده , , Eui Ta and Lee، نويسنده , , Min Hee and Park، نويسنده , , Yong Sun، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
Catalytic asymmetric dehydration of β-hydroxy esters via kinetic resolution has been investigated. The kinetic resolution of rac-β-hydroxy esters in the presence of prolinol chiral ligand 2a and BrZnCH2CO2t-Bu can provide highly enantioenriched β-hydroxy esters 3 and 5–11 with selectivity factors ranging from 15 to 42.
Keywords :
kinetic resolution , dehydration , Chiral catalyst , Flavonoids , alcohol , asymmetric syntheses
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
