Title of article
A simple one-pot procedure for the direct conversion of alcohols into azides using TsIm
Author/Authors
Soltani Rad، نويسنده , , Mohammad Navid and Behrouz، نويسنده , , Somayeh and Khalafi-Nezhad، نويسنده , , Ali، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
3445
To page
3449
Abstract
A facile and efficient method for one-pot conversion of alcohols into azides using N-(p-toluenesulfonyl)imidazole (TsIm) is described. In this method, alcohols are refluxed with a mixture of NaN3, TsIm and triethylamine in the presence of catalytic amounts of tetra-n-butylammonium iodide (TBAI) in DMF affording the corresponding alkyl azides in good yields. This methodology is highly efficient for various structurally diverse alcohols with selectivity for ROH: 1° > 2° > 3°.
Keywords
Azide , alcohol , N-(p-Toluenesulfonyl)imidazole (TsIm) , Triethylamine (TEA) , Tetrabutylammonium iodide (TBAI)
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1854946
Link To Document