Title of article
A new modular and flexible approach to [1,2,3]triazolo[1,5-a][1,4]benzodiazepines
Author/Authors
Pilar Sلnchez and Alajarيn، نويسنده , , Mateo and Cabrera، نويسنده , , José and Pastor، نويسنده , , Aurelia and Villalgordo، نويسنده , , José M.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
3495
To page
3499
Abstract
A new synthetic route for the access to [1,2,3]triazolo[1,5-a][1,4]benzodiazepines and other derivatives is described. This strategy is based on the cycloaddition of 2-oxoalkylidenephosphoranes to o-functionalized aryl azides followed by the reaction of the corresponding triazole intermediate with amines. This new approach presents unique properties such as regioselectivity, modularity, mild reaction conditions, and high yields.
Keywords
1 , 3-Triazole , Ketophosphorane , o-Functionalized aryl azide , Bis-electrophile , 2
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1854962
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