Title of article :
Chiral 1,3,6-trisubstituted 2,4-dioxohexahydropyrimidines: a convenient stereoselective synthesis from aspartic acid derivatives
Author/Authors :
Patiٌo-Molina، نويسنده , , Rosario and Cubero-Lajo، نويسنده , , Ivan and Pérez de Vega، نويسنده , , M. Jesْs and Garcيa-Lَpez، نويسنده , , M. Teresa and Gonzلlez-Muٌiz، نويسنده , , Rosario، نويسنده ,
Abstract :
Chiral 1,3,6-trisubstituted 2,4-dioxohexahydropyrimidines were easily synthesized by reaction of homoaspartic acid derivatives with isocyanates, followed by cyclization of the resulting urea, and alkylation at N1 position.
