Title of article
A variation of Mattox rearrangement mechanism under alkaline condition
Author/Authors
Li، نويسنده , , Min and Chen، نويسنده , , Bin and Lin، نويسنده , , Mingxiang and Chan، نويسنده , , Tze-Ming and Fu، نويسنده , , Xiaoyong and Rustum، نويسنده , , Abu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
3901
To page
3905
Abstract
A variation of the Mattox rearrangement, a key degradation pathway under acidic conditions for corticosteroids possessing the 1,3-dihydroxyacetone side chain, has been found to occur for the 17,21-diesters of these corticosteroids but under the alkaline condition. The mechanism of this variation of the original Mattox rearrangement is proposed.
Keywords
Corticosteroids , Mattox rearrangement , Betamethasone dipropionate , Degradation , Betamethasone enol aldehyde
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855094
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