Title of article
An efficient F-18 labeling method for PET study: Huisgen 1,3-dipolar cycloaddition of bioactive substances and F-18-labeled compounds
Author/Authors
Sirion، نويسنده , , Uthaiwan and Kim، نويسنده , , Hee-Jun and Lee، نويسنده , , Jae Hak and Seo، نويسنده , , Jai Woong and Lee، نويسنده , , Byoung Se and Lee، نويسنده , , Sang Ju and Oh، نويسنده , , Seung Jun and Chi، نويسنده , , Dae Yoon، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
3953
To page
3957
Abstract
The Cu(I)-catalyzed, 1,3-dipolar cycloaddition reaction was applied successfully to the synthesis of small, F-18-labeled biomolecules, and an optimal condition was developed for one-pot, two-step reaction without any interim purifications. This technique was employed in various F-18-labeled, 1,2,3-triazole syntheses with high radiochemical yield.
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855108
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