Title of article :
Piperazirum, a novel bioactive alkaloid from Arum palaestinum Boiss.
Author/Authors :
El-Desouky، نويسنده , , S.K. and Ryu، نويسنده , , Shi Young and Kim، نويسنده , , Young-Kyoon، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
A novel alkylated piperazine (3α,5α-diisobutyryl-6α-isopropyl-piperazine-2-one, 1) has been isolated from the n-butanol soluble part of the leaves extract of Arum palaestinum Boiss., the chemical structure and the relative stereochemistry of 1 were elucidated on the basis of 1D and 2D NMR spectroscopic data. Piperazirum showed a significant cytotoxicity against cultured tumor cell lines in vitro.
Keywords :
Arum palaestinum , cytotoxicity , 3? , NMR , Araceae , 5?-Diisobutyryl-6?-isopropyl-piperazine-2-one
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
