Title of article
A new approach for the construction of a highly congested bicyclic system in polycyclic polyprenylated acylphloroglucinols (PPAPs)
Author/Authors
Shimizu، نويسنده , , Yohei and Kuramochi، نويسنده , , Akiyoshi and Usuda، نويسنده , , Hiroyuki and Kanai، نويسنده , , Motomu and Shibasaki، نويسنده , , Masakatsu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
4173
To page
4177
Abstract
A highly congested bicyclo[3.3.1]nonanone core of polycyclic polyprenylated acylphloroglucinols was constructed using a stereoselective Claisen rearrangement and an intramolecular aldol reaction as the key steps. The stereochemistry of C-4 appeared to control the ground state conformation of the cyclohexenone core, which determined the diastereoselectivity in the Claisen rearrangement.
Keywords
garsubellin A , Polycyclic polyprenylated acylphloroglucinols (PPAPs) , Claisen rearrangement , intramolecular aldol reaction , hyperforin
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855182
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