Title of article
Total synthesis and morphogenesis-inducing activity of (±)-thallusin and its analogues
Author/Authors
Nishizawa، نويسنده , , Mugio and Iyenaga، نويسنده , , Tomoaki and Kurisaki، نويسنده , , Takahiro and Yamamoto، نويسنده , , Hirofumi and Sharfuddin، نويسنده , , Mohammed and Namba، نويسنده , , Kosuke and Imagawa، نويسنده , , Hiroshi and Shizuri، نويسنده , , Yoshikazu and Matsuo، نويسنده , , Yoshihide، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
4229
To page
4233
Abstract
Total synthesis of (±)-thallusin was achieved using Hg(OTf)2·PhNMe2-induced olefin cyclization, and Suzuki coupling with a pyridylboronic acid derivative. Hg(OTf)2 also acted as a catalyst to isomerize the double bond into the more thermodynamically stable isomer when treated in toluene. Synthetic (±)-thallusin as well as an analogue showed morphogenesis-inducing activity.
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855205
Link To Document