Title of article
Enzymatic kinetic resolution of racemic 4-tetrahydropyranols by Candida rugosa lipase
Author/Authors
Yadav، نويسنده , , J.S. and Reddy، نويسنده , , B.V.Subba and Padmavani، نويسنده , , B. and Venugopal، نويسنده , , Ch. and Rao، نويسنده , , A.Bhaskar، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
3
From page
4631
To page
4633
Abstract
Enzymatic kinetic resolution of (±)-hydroxytetrahydropyrans has been achieved for the first time by means of lipase-mediated transesterification to afford optically active (2S,4R)-tetrahydropyranyl acetates and (2R,4S)-tetrahydropyranols in excellent yields with high enantioselectivity. Absolute configurations of the tetrahydropyranyl acetates were assigned as (S) by chemical correlation.
Keywords
kinetic resolution , tetrahydropyranols , Lipase
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855405
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