Author/Authors :
Pridmore، نويسنده , , Simon J. and Slatford، نويسنده , , Paul A. and Daniel، نويسنده , , Aurélie and Whittlesey، نويسنده , , Michael K. and Williams، نويسنده , , Jonathan M.J. Williams، نويسنده ,
Abstract :
Various 1,2,5-substituted pyrroles have been synthesised from 1,4-alkynediols using a ruthenium catalysed isomerisation to give the corresponding 1,4-dicarbonyl compounds, which undergo in situ cyclisation to pyrroles in the presence of amine.