Ionic liquid supported synthesis of β-lactam library in ionic liquid batch

An efficient and general ionic liquid supported synthesis of cis-β-lactam library via multistep reactions have been successfully carried out in a single ionic liquid batch. The method exhibited the advantages over soluble and insoluble polymeric support strategies, such as high loading capacity, avoiding of large excesses of reagents and easy purification. Also, the products were obtained in good yields and purities.