Author/Authors :
Wang، نويسنده , , Ying and Sarris، نويسنده , , Kathy and Sauer، نويسنده , , Daryl R. and Djuric، نويسنده , , Stevan W.، نويسنده ,
Abstract :
Acylsulfonamides can be rapidly and conveniently synthesized from a variety of carboxylic acids and sulfonamides utilizing the commercially available reagents, PS-DCC and DMAP under mild reaction conditions. DMAP can be efficiently scavenged by utilization of a silica-supported tosic acid cartridge (Si-SCX). In most of the cases studied, products with high purities and yields were obtained without the need for further purification.
