Author/Authors :
Kikuchi، نويسنده , , Haruhisa and Nakamura، نويسنده , , Koji and Kubohara، نويسنده , , Yuzuru and Gokan، نويسنده , , Naomi and Hosaka، نويسنده , , Kohei and Maeda، نويسنده , , Yasuo and Oshima، نويسنده , , Yoshiteru، نويسنده ,
Abstract :
We have explored the diversity of secondary metabolites produced by cellular slime molds to evaluate if they are valuable resources for biologically potential substances. From the methanol extract of fruiting bodies of Dicyostelium firmibasis, we obtained new α-pyranoids, dihydrodictyopyrones A (1) and C (2). Their structures including absolute configurations were determined by spectral means and asymmetric total synthesis. Compounds 1 and 2 are new members of the dictyopyrone family, which are characteristic secondary metabolites of various species of Dictyostelium cellular slime molds.