Author/Authors :
Ahmad، نويسنده , , Simon M. and Braddock، نويسنده , , D. Christopher and Cansell، نويسنده , , Gemma and Hermitage، نويسنده , , Stephen A. and Redmond، نويسنده , , Joanna M. and White، نويسنده , , Andrew J.P.، نويسنده ,
Abstract :
(±)-iso-Amarine is a potent organocatalyst at 1 mol % loading for both the bromoacetoxylation of alkenes with added acetic acid and bromolactonisation of unsaturated carboxylic acids with stoichiometric NBS as the electrophilic bromine source. A simple bromoamidine with an N–Br bond has been characterised crystallographically for the first time. Asymmetric induction in the bromination reactions with enantiopure amidines was zero.
Keywords :
alkenes , Electrophilic bromination , organocatalysis , Amidine
