Title of article
Microwave-assisted, zinc-mediated peptide coupling of N-benzyl-α,α-disubstituted amino acids
Author/Authors
Cianci، نويسنده , , Julia and Baell، نويسنده , , Jonathan B. and Harvey، نويسنده , , Andrew J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
3
From page
5973
To page
5975
Abstract
Incorporation of the extremely hindered amino acid N-benzylaminoisobutyric acid into dipeptides under microwave irradiation with commercial zinc dust is described. A comparative survey of various methodologies for hindered peptide couplings was undertaken. The optimised coupling conditions were free from racemisation and applicable to other hindered amino acids.
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1856106
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