Title of article :
On the synthesis of β-bromohydrine ethers via intermolecular alkoxyl radical addition to bicyclo[2.2.1]heptene
Author/Authors :
Hartung، نويسنده , , Jens and Schneiders، نويسنده , , Nina and Gottwald، نويسنده , , Thomas، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
Primary, secondary, and tertiary alkoxyl radicals add exo-selectively to the olefinic π-bond in bicyclo[2.2.1]heptene to afford exo-2-alkoxybicyclo[2.2.1]hept-3-yl radicals, which are trapped with BrCCl3 preferentially from the endo face to furnish β-bromohydrine ethers in 23–67% yield.
Keywords :
Alkoxyl radical , Homolytic bromination , stereoselective synthesis , Tertiary thiohydroxamic acid O-esters , Intermolecular addition
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
