Author/Authors :
Marzorati، نويسنده , , Liliana and Barazzone، نويسنده , , Giovana C. and Bueno Filho، نويسنده , , Marco A. and Wladislaw، نويسنده , , Blanka and Di Vitta، نويسنده , , Claudio، نويسنده ,
Abstract :
N-Tosyl aziridine-2-carboxylate methyl esters were prepared from methyl N-tosyl-l-serinate or N-tosyl-l-threoninate, tosyl chloride, and K2CO3, under phase-transfer catalysis (PTC) conditions. The same methodology, as applied to the tert-butyl N-tosyl-l-serine amide, afforded the corresponding newly prepared aziridine-2-carboxamide, as an enantiomerically pure compound.
