Title of article
Copper-catalyzed one-pot N-alkenylation and N-alkylation of amides: an efficient synthesis of substituted 2,3-dihydropyrroles
Author/Authors
Zhou، نويسنده , , Xiaobo and Zhang، نويسنده , , Huimin and Yuan، نويسنده , , Jiwei and Mai، نويسنده , , Lugen and Li، نويسنده , , Yanzhong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
7236
To page
7239
Abstract
A novel copper-catalyzed synthesis of substituted 2,3-dihydropyrroles via one-pot N-alkenylation and N-alkylation of amides with 1,4-diiodobut-1-ene derivatives has been developed. The reactions proceed in good to high yields using CuI as the catalyst, K2CO3 as the base, and rac-trans-N,N′-dimethylcyclohexane-1,2-diamine as the ligand.
Keywords
copper catalyst , N-Alkenylation , N-Alkylation , Amides , dihydropyrroles
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1856765
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