Title of article
A convenient synthesis of 1,2,4-trisubstituted azetidines by reductive cyclization of aza-Michael adducts of chalcones
Author/Authors
Yadav، نويسنده , , Lal Dhar S. and Awasthi، نويسنده , , Chhama and Rai، نويسنده , , Vijai K. and Rai، نويسنده , , Ankita، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
3
From page
8037
To page
8039
Abstract
Aza-Michael adducts of chalcones and diethyl N-arylphosphoramidates undergo reductive cyclization with sodium borohydride followed by sodium hydride to afford 1,2,4-trisubstituted azetidines diastereoselectively in a one-pot procedure and excellent yields.
Keywords
azetidines , Michael addition , Chalcones , Phosphoramidates , Reduction , Cyclization reactions
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1857194
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