Title of article :
A simple method for the alkaline hydrolysis of esters
Author/Authors :
Theodorou، نويسنده , , Vassiliki and Skobridis، نويسنده , , Konstantinos and Tzakos، نويسنده , , Andreas G. and Ragoussis، نويسنده , , Valentine، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
A very mild and rapid procedure for the efficient alkaline hydrolysis of esters in non-aqueous conditions has been developed, by the use of dichloromethane/methanol (9:1) as solvent. This method conveniently provides both carboxylic acids and alcohols from the corresponding esters and sodium hydroxide in a few minutes at room temperature. A plausible reaction mechanism is proposed.
Keywords :
Saponification of esters , Mechanism , Methanolysis , Non-aqueous conditions , Selective enrichment of COOH , carboxylic acids , alcohols
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
